Heat a large Pot or Dutch Oven over medium-high heat. Add the 2 lb ground beef 80/20 for best flavor and cook, breaking it up with a Wooden Spoon, until browned and no longer pink, about 7–8 minutes. Drain excess fat if desired, leaving about 1 tbsp in the pot for flavor.

Reduce heat to medium. Add the diced 1 medium yellow onion diced and 1 medium green bell pepper diced to the Pot and cook, stirring occasionally, until softened, about 5 minutes. Add the 4 cloves garlic minced and cook for 1 more minute until fragrant.

Stir in the 1 can crushed tomatoes and all the spices (2 tbsp chili powder, 1 ½ tsp ground cumin, 1 tsp smoked paprika, ½ tsp cayenne pepper adjust, 1 tsp dried oregano, 1 tsp salt, and ½ tsp black pepper freshly ground). Cook for 1–2 minutes, stirring constantly, to bloom the spices and deepen the flavor.

Pull the brisket from the Refrigerator 30 to 60 minutes before cooking to let it approach room temperature. Trim hard fat down to about a quarter inch. Apply your dry rub or salt-and-pepper blend evenly over the whole surface, pressing it in firmly. Soak Wood Chips in water for at least 30 minutes if your Smoker uses chips, or prep wood chunks and pellets per your smoker's directions. Empty the drip tray before you start. Set aside unwaxed Butcher Paper or heavy-duty Aluminum Foil for wrapping later in the cook.

Preheat your Smoker to 225–250°F and verify the temperature with a standalone Meat Thermometer. Add Wood Chips, chunks, or pellets per your smoker's instructions. Place the brisket fat side up with the point end toward the heat source. Close the smoker and avoid opening it often. Check wood and adjust vents every 45 minutes to hold 225–250°F. Rotate the brisket every 3 hours and flip if one side colors faster. Smoke uncovered until the internal temperature hits 165°F and a dark bark has formed, about 5 to 8 hours. Wrap tightly in Butcher Paper or Aluminum Foil, return to the smoker, and continue until an Instant-Read Thermometer reads 195–203°F and the meat is very tender but not falling apart, roughly 4 to 5 more hours. Total cook time is typically 8 to 12 hours. Use internal temperature and texture as your doneness cues, not the clock alone.